Guo Gan started learning erhu in early childhood from his father Guo Jun Ming, also a renowned erhu master .
In 2000, Guo Gan went to France to study and later obtained Master's degree from the National Music School of Fresnes in Paris. During this period, he founded first Chinese Jazz band - Dragon Jazz in Paris and won the second place at the European Chinese musician competition in Belgium in December 2002.
Through Chinese traditional erhu art, Guo Gan has worked with many musicians and artists in different parts of the world and travelled to more than 70 countries. He has played in nearly 2000 concerts and published more than 40 albums. He has performed at many famous concert halls of the world such as New York's Carnegie Hall, New York's Lincoln Hall, the Chicago Sympnony Hall, the Royal Music Hall in Geneva, the Paris City Hall, the Palais des Congres and many others.
Guo Gan has played with many of the world's most famous musician including Lang Lang, Yvan Cassar, Didier Lockwood and Jean Francois Zyge!. His performances with Lang Lang in Europe and the US have not only been highly recognised and praised by the media, but also gained popularity among music lovers around the world. In 2005, he played the symphonic poem 'Chinese Ink' with Yvan Casser, a well-known French conductor. He has performed with world's top orchestras as well.
He has also been involved in different areas of music such as world music, classical music, jazz, ballet, opera, modern music, film music and, pop music. He has been highly recognised by the media Steve Smith, editor of the New York Times Arts Page wrote, 'Mr Guo, a magnificent performer, shaped melodies with the expressive contours of vocal lines in Hua Yanjun's "Moon reflected on the Er-Quan Spring" and provided flourishes that might give a violinist pause during Huang Gaihuai's "Horse Racing".' Mark Swed, music critic for the Los Angles Times, also gave high regard to Guo Gan's performance with Lang Lang: 'Guo was a wonder, his Erhu sweetly filling the air with an astonishing sweet and sumptuous sonic perfume, which Lang accompanied with exquisite sensitivity.'
Television and radio stations have, for many times, conducted personal interviews with Guo Gan, referring to him as 'the master of two strings'. In the eyes of the French media, he has become a symbol of the Chinese erhu. In France in 2011 an article was written about him citing him as 'the King of Chinese erhu'. During the past 12 years in France, Guo Gan has been a missionary of Sino-French culture exchange. He has also played on behalf of the French Culture Ministry in Zhou Zhuang in China and at the French Pavilion at the Shanghai EXPO.
Besides his ardent pursuit of music, Guo Gan has been actively participating in charitable works around the world. In the past few years, he played at events organised by UNESCO, for instance, working with Tan Dun, the famous Chinese composer in 2012 in Hangzhou Grand/Theatre, promoting the theme of cherishing the word's water resources. He has also worked with Lang Lang in Shenzhen at a themed performance to promote world peace. He has played for free for children in poverty in Africa, South American and remote regions in China.